It supports work via ADS adapter (version 1, not for all ECUs) as well as via any J2534-compatible adapter if there are appropriate drivers and libraries.
There are universal modules Denso SH705x Bootloader and BSL TriCore. PCMflash is an integrated software solution intended for reprogramming ECUs and TCUs of Volkswagen, Skoda, Ford, Mazda, Mitsubishi, Nissan/Infiniti, Subaru, Honda/Acura, Hyundai/Kia, Renault, Toyota/Lexus and other vehicles.